CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17866
Family Name Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibitor SureCN3569311 family
No. of Seeds 1 No. of Other Members 12
Family Centroid CFAMM00444775 Functional Category Bioactive with Natural Product
Superfamily Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibitor SureCN3569311 Superfamily
Class Class 3477

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(o... 4 4
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Prostaglandin D2 receptor 2 ligand 2-[1-[4-[(4-methoxybenzoyl)... 2 2
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 2 10
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444775 CHEMBL489445 Bioactive SureCN3569311

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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