CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17869
Family Name Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family
No. of Seeds 8 No. of Other Members 1
Family Centroid CFAMM00444791 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Diacylglycerol O-acyltransferase 1 Binder Superfamily
Class Class 1456

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Eluxadoline family 4 85
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-... 2 15
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
5-hydroxytryptamine receptor 4 ligand AGN-PC-00PM3Y family 4 3
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Mitogen-activated protein kinase 14 inhibitor methyl 4-[5-(eth... 3 11
Neuropeptide Y receptor type 5 ligand AGN-PC-07R6YQ family 7 7
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Vascular endothelial growth factor receptor 2 and Fibroblast g... 1 6
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
Histamine H3 receptor ligand AGN-PC-075YVW family 1 2
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
Neuropeptide Y receptor type 5 ligand AGN-PC-077LY9 family 5 5
Neuropeptide Y receptor type 5 ligand 1'-(5H-[1,3]dioxolo[4,5-... 2 1
Neuropeptide Y receptor type 5 ligand 1'-(5-CHLORO-1H-BENZIMID... 4 1
Neuropeptide Y receptor type 5 ligand AGN-PC-02WBQH family 7 1
Neuropeptide Y receptor type 5 ligand AGN-PC-077LYW family 3 1
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Cannabinoid receptor 2 ligand [(4S,4aR,8aS)-4-hydroxy-4-phenyl... 1 0


External ID

Functional Category

Molecule Name

CFAMM00444788 CHEMBL522768 Bioactive AGN-PC-03I9SP
CFAMM00444795 CHEMBL491229 Bioactive SureCN2889580
CFAMM00444787 CHEMBL491230 Bioactive AGN-PC-077LXC
CFAMM00444794 CHEMBL491427 Bioactive AGN-PC-077LXD
CFAMM00444792 CHEMBL524644 Bioactive AGN-PC-077MJR
CFAMM00444791 CHEMBL489587 Bioactive AGN-PC-077LX1
CFAMM00444790 CHEMBL521959 Bioactive AGN-PC-077LXE
CFAMM00444789 CHEMBL496327 Bioactive AGN-PC-02WBQQ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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