CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17873
Family Name 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2C ligand [3-(2-fluoroethoxy)-2-methoxyphenyl]-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanone family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00057859 Functional Category Bioactive
Superfamily Acetylcholinesterase Inhibitor Taspine Superfamily
Class Class 2572

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Steryl-sulfatase Inhibitor Sulfamic Acid 2-nonyl-4-oxo-4h-chro... 4 68
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Sodium-dependent dopamine transporter and Sigma non-opioid int... 7 5
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 8
Histamine H1 receptor ligand Ahr 5333 family 1 6
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
Acetylcholinesterase and Butyrylcholinesterase inhibitor 2-[4-... 3 2
Histamine H1 receptor and Cysteinyl leukotriene receptor 1 lig... 1 15
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444853 CHEMBL489624 Bioactive AGN-PC-03U0IF

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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