CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17884
Family Name P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(2,4-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide family
No. of Seeds 3 No. of Other Members 26
Family Centroid CFAMM00444939 Functional Category Bioactive
Superfamily Prelamin-A/C and P2X purinoceptor 7 Binder Superfamily 2
Class Class 1059

Cousin Family NamesSeedsMembers
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Potassium ... 1 15
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 7
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444932 CHEMBL490118 Bioactive N-[1-[(Z)-[(2-chloroanilino)-(cyanoamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
CFAMM00444934 CHEMBL490117 Bioactive N-[1-[(Z)-[(cyanoamino)-(2,5-dimethylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
CFAMM00444939 CHEMBL524108 Bioactive N-[1-[(Z)-[(cyanoamino)-(2,4-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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