CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17886
Family Name Sodium-dependent serotonin transporter inhibitor 1-[5-methoxy-2-(4-methylsulfanylphenoxy)phenyl]-N,N-dimethylmethanamine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00444944 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Histamine H3 receptor Binder Superfamily
Class Class 1931

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Dapoxetine family 3 40
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Dipeptidyl peptidase 4 Inhibitor (2-chloro-6-phenoxyphenyl)met... 17 24
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 13 2
Sodium-dependent serotonin transporter and Histamine H3 recept... 2 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-077LP1... 3 5
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
Sodium-dependent serotonin transporter inhibitor 3-[(DIMETHYLA... 5 1


External ID

Functional Category

Molecule Name

CFAMM00444944 CHEMBL490205 Bioactive 1-[5-methoxy-2-(4-methylsulfanylphenoxy)phenyl]-N,N-dimethylmethanamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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