CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17895
Family Name Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 inhibitor AGN-PC-077NUM family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00385638 Functional Category Bioactive with Natural Product
Superfamily Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 2498

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Tyrosine-protein kinase SYK and Low affinity immunoglobulin ep... 1 0
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 1 18
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 11 11
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 1
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 0
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 3 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 4 4
Substance-P receptor ligand SureCN2139814 family 7 7
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Glycogen synthase kinase-3 beta inhibitor bip-135 family 3 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
Vascular endothelial growth factor receptor 2 ligand (4Z)-4-[(... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444972 CHEMBL564450 Bioactive SureCN5260235
CFAMM00444970 CHEMBL490842 Bioactive AGN-PC-077NV6
CFAMM00444969 CHEMBL490636 Bioactive AGN-PC-077NV4
CFAMM00444968 CHEMBL491647 Bioactive AGN-PC-077NUO

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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