CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17934
Family Name Mitogen-activated protein kinase 14 and Tyrosine-protein kinase Lyn inhibitor SureCN393435 family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00445135 Functional Category Bioactive
Superfamily Cathepsin K and Beta-lactamase Binder Superfamily
Class Class 4739

Cousin Family NamesSeedsMembers
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Beta-secretase 1 inhibitor SureCN8284176 family 2 4
Huntingtin and Niemann-Pick C1 protein inhibitor CHEMBL1453691... 1 7
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 3 8
Sodium-dependent dopamine transporter and Transporter inhibito... 3 3
Growth hormone secretagogue receptor type 1 ligand 2-(4-methox... 1 0


External ID

Functional Category

Molecule Name

CFAMM00445144 CHEMBL493708 Bioactive SureCN395967
CFAMM00445135 CHEMBL493671 Bioactive SureCN393435
CFAMM00445141 CHEMBL522579 Bioactive N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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