CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1798
Family Name Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor SureCN8259136 family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00327520 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Dipeptidyl peptidase 9 Binder Superfamily
Class Class 3039

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 18 41
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor AG... 5 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Tyrosine-protein kinase JAK2 inhibitor N-[2-(3-chlorophenyl)-5... 2 11
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 5-(2-... 6 83
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 19
Cannabinoid receptor 1 ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 5-(2-... 12 1
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
Sodium- and chloride-dependent glycine transporter 1 and Sodiu... 4 8
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 3 1
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Tyrosine-protein kinase JAK2 and Cytochrome P450 3A4 inhibitor... 1 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Histone deacetylase 1 and Proto-oncogene tyrosine-protein kina... 4 0
Adenosine receptor A2b ligand N-(4-chlorophenyl)-2-[(5Z)-5-(2,... 1 2
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
Cannabinoid receptor 1 ligand N-(3,3a,4,5,6,6a-hexahydro-1H-cy... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Cannabinoid receptor 1 ligand AGN-PC-077JWI family 7 1
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Cannabinoid receptor 1 ligand AGN-PC-07R6O8 family 5 2
Cannabinoid receptor 1 ligand AGN-PC-07RA6C family 21 2
Cannabinoid receptor 1 ligand AGN-PC-07RA3R family 15 0
Cannabinoid receptor 1 ligand AGN-PC-07R9T4 family 27 0
Acyl-CoA desaturase 1 inhibitor AGN-PC-09QJVI family 2 0
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Adenosine receptor A2b ligand N-[(3Z)-3-(2,6-dioxo-1,3-dipropy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327518 CHEMBL1215233 Bioactive AGN-PC-07ZN6X
CFAMM00327515 CHEMBL1760690 Bioactive AGN-PC-0A9T7I
CFAMM00327521 CHEMBL1215165 Bioactive AGN-PC-07ZN2A
CFAMM00327520 CHEMBL1215089 Bioactive SureCN8259136
CFAMM00327519 CHEMBL1215234 Bioactive AGN-PC-07ZN6Y

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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