CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17981
Family Name Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhibitor AGN-PC-077O2B family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00445291 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 Binder Superfamily
Class Class 216

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 23
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
Histamine H3 receptor Ligand A-349821 Family 49 228
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 10
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 1 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
C-C chemokine receptor type 1 ligand SureCN8184421 family 11 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
D(3) dopamine receptor ligand S33084 family 1 1


External ID

Functional Category

Molecule Name

CFAMM00445292 CHEMBL496189 Bioactive 4-oxo-N-[(1S,2R)-2-phenylcyclopropyl]spiro[3H-chromene-2,4'-piperidine]-1'-carboxamide
CFAMM00445291 CHEMBL519149 Bioactive AGN-PC-077O2B
CFAMM00445290 CHEMBL495601 Bioactive AGN-PC-077O5D

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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