CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17997
Family Name Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhibitor 4-oxo-N-[(1S,2R)-2-phenylcyclopropyl]-6-pyridin-4-ylspiro[3H-chromene-2,4'-piperidine]-1'-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00445351 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 and Aldose reductase Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Aromatase Inhibitor 2-phenyl-3-pyridin-4-ylmethylene-chroman-4... 3 30
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 1
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Bifunctional epoxide hydrolase 2 and Voltage-dependent L-type ... 2 1
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445351 CHEMBL495992 Bioactive 4-oxo-N-[(1S,2R)-2-phenylcyclopropyl]-6-pyridin-4-ylspiro[3H-chromene-2,4'-piperidine]-1'-carboxamide
CFAMM00445350 CHEMBL495993 Bioactive 4-oxo-N-[(1S,2R)-2-phenylcyclopropyl]spiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-1'-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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