CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18002
Family Name Serine/threonine-protein kinase B-raf and RAF proto-oncogene serine/threonine-protein kinase inhibitor GDC-0879 family
No. of Seeds 10 No. of Other Members 2
Family Centroid CFAMM00445354 Functional Category Bioactive
Superfamily TGF-beta receptor type-1 and Hepatocyte growth factor receptor Binder Superfamily
Class Class 1666

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
TGF-beta receptor type-1 Ligand 4-(3-pyridin-2-yl-1h-pyrazol-4... 3 63
Corticotropin-releasing factor receptor 1 ligand 3,7-dimethyl-... 3 4
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00CFYH ... 2 1
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00AP1L ... 14 7
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(2-meth... 7 9
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 1
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 6
Serine/threonine-protein kinase Chk1 inhibitor 5-[7-(2-morphol... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3
Sigma non-opioid intracellular receptor 1 ligand 1-phenyl-4-(2... 1 0
Serine/threonine-protein kinase B-raf and Mitogen-activated pr... 16 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445385 CHEMBL498344 Bioactive (1S,3R)-3-[4-[(1E)-1-hydroxyimino-2,3-dihydroinden-5-yl]-3-pyridin-4-ylpyrazol-1-yl]cyclohexan-1-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26843 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543