CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18008
Family Name Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylamino]quinazoline-6-carboxylic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00445401 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Niemann-Pick C1 protein Binder Superfamily
Class Class 4316

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Aurora kinase A Inhibitor MLN8054 Family 2 5
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 1-methyl-8-(... 1 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 30
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Adenosine receptor A1 ligand AGN-PC-07PMLW family 6 4
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Prostaglandin D2 receptor ligand 2-[3-[6-[2-(2,4-dichloropheny... 7 2
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 2-[3-[... 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Type-1B angiotensin II receptor ligand SureCN9310003 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445401 CHEMBL49663 Bioactive 2-ethyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylamino]quinazoline-6-carboxylic acid
CFAMM00445400 CHEMBL49715 Bioactive 4-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]quinazoline-6-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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