CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18029
Family Name P2X purinoceptor 7 inhibitor N'-quinolin-5-yladamantane-1-carbohydrazide family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00445550 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Prelamin-A/C Binder Superfamily
Class Class 3984

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Neuromedin-K receptor Ligand SB222200 Family 17 235
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Lethal factor Inhibitor GM6001 Family 50 435
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
Histone deacetylase 1 inhibitor AGN-PC-0456JP family 1 0
P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(quinolin... 3 3
Retina-specific copper amine oxidase inhibitor 2-(3-pyrrol-1-y... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445545 CHEMBL523873 Bioactive 3-chloro-N'-quinolin-5-yladamantane-1-carbohydrazide
CFAMM00445550 CHEMBL497967 Bioactive N'-quinolin-5-yladamantane-1-carbohydrazide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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