CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18057
Family Name Hepatocyte growth factor receptor and Cytochrome P450 3A4 ligand N-[[4-(2-amino-3-ethynylpyridin-4-yl)oxy-3-fluorophenyl]carbamoyl]-2-(4-fluorophenyl)acetamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00264386 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Peptidyl-prolyl cis-trans isomerase A Binder Superfamily
Class Class 1612

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Smoothened homolog Inhibitor LDE225 Family 3 76
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 10
E7050 family 2 13
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Hepatocyte growth factor receptor Ligand BMS-777607 Family 10 1
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Hepatocyte growth factor receptor ligand SureCN4492034 family 2 2
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Corticotropin-releasing factor receptor 1 ligand AGN-PC-009TSL... 3 3
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Motilin receptor ligand SureCN2765637 family 1 1
Hepatocyte growth factor receptor ligand 4-pyridone analogue, ... 8 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Hepatocyte growth factor receptor ligand AGN-PC-077PZW family 1 0
Acyl-CoA desaturase inhibitor SureCN1182546 family 2 5
Acyl-CoA desaturase inhibitor SureCN1182719 family 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6
Tyrosine-protein kinase receptor Tie-1 and Receptor-type tyros... 1 0
Transient receptor potential cation channel subfamily V member... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445665 CHEMBL526929 Bioactive AGN-PC-04XP7P
CFAMM00445664 CHEMBL500422 Bioactive AGN-PC-04XOQP
CFAMM00445666 CHEMBL525049 Bioactive AGN-PC-04XP7T

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26400 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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