CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18118
Family Name Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene receptor 1 ligand 4-[[1-[(3-cyanophenyl)methyl]-5-[(2-cyclopentylacetyl)amino]indol-3-yl]methyl]-3-methoxybenzoic acid family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00445887 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 and Glycogen synthase kinase-3 beta Binder Superfamily
Class Class 2498

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Indeglitazar family 3 39
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Tyrosine-protein kinase SYK and Low affinity immunoglobulin ep... 1 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Prostaglandin D2 receptor 2 ligand SureCN137822 family 3 0
Integrase inhibitor (Z)-4-[1-[(4-fluorophenyl)methyl]-5-methox... 1 0
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 5 2
Pol polyprotein inhibitor Phenprocoumon IndolEtCONH deriv. family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445887 CHEMBL51061 Bioactive 4-[[1-[(3-cyanophenyl)methyl]-5-[(2-cyclopentylacetyl)amino]indol-3-yl]methyl]-3-methoxybenzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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