CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18130
Family Name Sodium-dependent dopamine transporter inhibitor 2-(4-aminophenyl)ethyl (1R,3S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00445931 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor Ligand RTI-76 Superfamily
Class Class 367

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Anileridine Family 3 18
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Type-1 angiotensin II receptor Ligand RTI-76 Family 3 6
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 11 20
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 5
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent dopamine transporter inhibitor methyl (1R,3S)... 1 0
Sodium-dependent dopamine transporter inhibitor 2-[4-[(2-bromo... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445931 CHEMBL51223 Bioactive 2-(4-aminophenyl)ethyl (1R,3S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00445930 CHEMBL607091 Bioactive 2-(4-amino-3-iodophenyl)ethyl (1R,3S,4S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00445929 CHEMBL607094 Bioactive 2-(4-aminophenyl)ethyl (1R,3S,4S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00445928 CHEMBL607150 Bioactive 2-(4-nitrophenyl)ethyl (1R,3S,4S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00445932 CHEMBL607260 Bioactive 2-(4-azidophenyl)ethyl (1R,3S,4S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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