CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18146
Family Name Neprilysin and Angiotensin-converting enzyme inhibitor 3-[(3S)-3-[[(2S)-2-benzyl-3-sulfanylpropanoyl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]propanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00060241 Functional Category Bioactive
Superfamily Neprilysin and Angiotensin-converting enzyme Binder Superfamily
Class Class 3095

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Motilin receptor Ligand GSK962040 Family 30 457
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Neprilysin Inhibitor Thiorphan Family 41 68
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Leukotriene A-4 hydrolase Inhibitor SA-6541 Family 4 32
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 5
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(2-a... 2 8
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Angiotensin-converting enzyme inhibitor (2S)-1-[(2S)-2-sulfany... 7 23
Pol polyprotein inhibitor Lysine Sulfonamide 11o family 2 6
Mitogen-activated protein kinase 1 and M17 leucyl aminopeptida... 1 21
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Dipeptidyl peptidase 4 inhibitor SureCN1499864 family 4 7
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 3 5
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Angiotensin-converting enzyme inhibitor (2S)-2-[[(3R)-5-(carbo... 6 4
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 4 2
Growth hormone secretagogue receptor type 1 ligand SureCN77944... 1 2
Granzyme B and Caspase-3 inhibitor CHEMBL304368 family 2 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Caspase-8 and Caspase-3 inhibitor (3S)-3-[[(2S)-4-methyl-2-[[2... 3 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Angiotensin-converting enzyme inhibitor 89177-63-9 family 2 0
Acyl-CoA:cholesterol acyltransferase inhibitor N-[2,6-di(propa... 1 2
2-[[(2S)-2-[(3-oxo-2,4-dihydroquinoxaline-1-carbonyl)amino]-3-... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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