CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18156
Family Name 5-hydroxytryptamine receptor 2B ligand SureCN1299053 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00445981 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 Binder Superfamily
Class Class 2756

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Histamine H1 receptor Ligand Mizolastine Family 14 603
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Tryptase Inhibitor Babim Family 12 90
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Adenosine receptor A3 Ligand 2-(4-nitro-1h-benzo[d]imidazol-2-... 2 12
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 8
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Type-1 angiotensin II receptor ligand AGN-PC-075NNL family 1 1
Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... 4 4
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Histamine H4 receptor ligand (2Z)-5-chloro-2-[(1-methylpiperid... 2 8
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Thymidylate synthase inhibitor AGN-PC-003VKA family 1 1
Thymidylate synthase inhibitor AGN-PC-003VK7 family 1 4
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Cannabinoid receptor 2 ligand 2-tert-butyl-5-ethylsulfonyl-1-(... 28 32
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Cyclin-dependent kinase 1 inhibitor 4-[[4-(3H-benzimidazol-5-y... 1 0
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 ligand ... 8 19
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
High affinity nerve growth factor receptor ligand N-[3-amino-5... 4 10
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 1
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Neuropeptide Y receptor type 5 ligand 2-(2,2-difluoro-2-phenyl... 2 2
Neuropeptide Y receptor type 5 ligand (6-ethylsulfonyl-1H-benz... 1 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-0CSEAG family 2 1
Cannabinoid receptor 2 ligand 4-[[2-tert-butyl-1-(cyclohexylme... 2 0
Type-1 angiotensin II receptor ligand SureCN7390271 family 2 1
Tyrosine-protein phosphatase non-receptor type 1 ligand sodium... 1 44
Gonadotropin-releasing hormone receptor ligand 4-[[4-[2-(4-ter... 3 3
Nuclear receptor subfamily 1 group I member 2 ligand AGN-PC-07... 2 13
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor ZINC00... 1 0
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0
D(2) dopamine receptor and D(4) dopamine receptor ligand 3-[1-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00445981 CHEMBL514934 Bioactive SureCN1299053

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543