CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18159
Family Name C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[(3,4-dichlorophenyl)methylcarbamoyl-ethylamino]piperidin-1-yl]-1-phenylbutyl]cyclobutanecarboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00446000 Functional Category Bioactive
Superfamily Neuromedin-K receptor Ligand Osanetant Superfamily
Class Class 908

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 4 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Substance-P receptor ligand AGN-PC-075NUD family 4 1
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 9 0
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 2 0
Neuromedin-K receptor ligand (1S,2R)-1-(3,4-dichlorophenyl)-N-... 8 0
Prothrombin inhibitor AGN-PC-09QJ23 family 2 5
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 7 31
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Lysosomal Pro-X carboxypeptidase inhibitor (2S,3S)-2-[(2-amino... 3 3
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 3
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 1
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 6 0
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 1
Neuromedin-K receptor and Substance-K receptor ligand AGN-PC-0... 2 0
Histamine H3 receptor ligand (2S)-N-[(3,4-dichlorophenyl)methy... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446000 CHEMBL515193 Bioactive N-[(1S)-3-[4-[(3,4-dichlorophenyl)methylcarbamoyl-ethylamino]piperidin-1-yl]-1-phenylbutyl]cyclobutanecarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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