CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18165
Family Name Collagenase 3 and Interstitial collagenase inhibitor (2R,3S)-N-[(2S)-3-[4-(diaminomethylideneamino)phenyl]-1-(methylamino)-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(3-phenylpropyl)butanediamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00446026 Functional Category Bioactive
Superfamily Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glutamamide Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Pan-DAC Inhibitor AR-42 Family 21 153
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 9 19
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
Cathepsin K and Cathepsin B inhibitor AGN-PC-01Z23J family 2 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(cyanomethyl)-... 1 6
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-037CNR f... 5 8
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 4 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Tryptase alpha/beta-1 and Tryptase delta inhibitor SureCN75047... 4 2
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446026 CHEMBL516206 Bioactive (2R,3S)-N-[(2S)-3-[4-(diaminomethylideneamino)phenyl]-1-(methylamino)-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(3-phenylpropyl)butanediamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26824 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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