CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18171
Family Name Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-078W6F family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00416878 Functional Category Bioactive
Superfamily Platelet-activating factor receptor and Beta-lactamase Binder Superfamily
Class Class 1256

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
Mitogen-activated protein kinase 14 Inhibitor CP-808844 Family 39 43
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 6
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Adenosine receptor A2a ligand SureCN6867940 family 13 13
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 9 inhibitor Su... 3 1
DNA-(apurinic or apyrimidinic site) lyase and Nuclear receptor... 2 10
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 8 0
Adenosine receptor A3 and Adenosine receptor A2b ligand CHEMBL... 5 0
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 7 4
Prelamin-A/C and Ferritin light chain inhibitor F2515-0416 family 2 4
Mu-type opioid receptor ligand Mirfentanil family 1 0
Adenosine receptor A2a ligand 5-N-[[(2R)-1-[(2-chloro-3,6-difl... 7 9
Adenosine receptor A2a ligand 5-[[[(2R)-1-[(2-chloropyridin-4-... 5 0
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Adenosine receptor A2a ligand 7-(3,4-dimethoxyphenyl)-2-(furan... 6 1
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 5
Adenosine receptor A3 ligand CHEMBL1834703 family 2 1
Vascular endothelial growth factor receptor 1 and Vascular end... 11 38
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 0
Tyrosine-protein kinase SYK inhibitor 4-[[3-[8-[(5,6-dimethoxy... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 6
Vascular endothelial growth factor receptor 2 and Platelet-der... 16 11
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 0
Adenosine receptor A2a and Adenosine receptor A1 ligand 5-[(7S... 6 1
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 4
Vascular endothelial growth factor receptor 2 ligand AGN-PC-04... 8 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 3
Adenosine receptor A2a ligand 3-[(2-bromophenyl)methyl]-8-(fur... 2 0
Adenosine receptor A2a ligand 8-(furan-2-yl)-3-[2-[4-(1,3-thia... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 25 5
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 29 1
Adenosine receptor A2a and Adenosine receptor A1 ligand 1-[(2-... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 1 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 1 0
Adenosine receptor A2a ligand SureCN8368237 family 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 2
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 1 0
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 1 12


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446035 CHEMBL517867 Bioactive AGN-PC-050CIS

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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