CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1818
Family Name Type-1 angiotensin II receptor and Type-2 angiotensin II receptor ligand 2-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyridine-3-carboxylic acid family
No. of Seeds 16 No. of Other Members 34
Family Centroid CFAMM00327789 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-2 angiotensin II receptor Binder Superfamily 2
Class Class 3453

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Progesterone receptor Ligand GSK-325971A Family 1 13
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 30
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 9 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0
Type-1B angiotensin II receptor ligand SureCN9310003 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327776 CHEMBL416477 Bioactive 141887-34-5
CFAMM00327789 CHEMBL125218 Bioactive 2-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyridine-3-carboxylic acid
CFAMM00327762 CHEMBL327488 Bioactive 2-[pentyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyridine-3-carboxylic acid
CFAMM00327794 CHEMBL89484 Bioactive SureCN9590303
CFAMM00327807 CHEMBL92256 Bioactive SureCN9591506
CFAMM00327800 CHEMBL91255 Bioactive SureCN9590263
CFAMM00327780 CHEMBL432827 Bioactive SureCN9589686
CFAMM00327793 CHEMBL329212 Bioactive SureCN9590192
CFAMM00327806 CHEMBL327784 Bioactive SureCN9591336
CFAMM00327773 CHEMBL88371 Bioactive SureCN9590432
CFAMM00327786 CHEMBL440521 Bioactive 2-[ethyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyridine-3-carboxylic acid
CFAMM00327805 CHEMBL89404 Bioactive SureCN9589750
CFAMM00327772 CHEMBL314999 Bioactive AGN-PC-02K5GW
CFAMM00327810 CHEMBL329611 Bioactive SureCN9590789
CFAMM00327764 CHEMBL92062 Bioactive SureCN9591631
CFAMM00327770 CHEMBL121635 Bioactive SureCN9589602

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26843 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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