CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18198
Family Name Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-04XL74 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00446074 Functional Category Bioactive
Superfamily Beta-lactamase and Prelamin-A/C Binder Superfamily 14
Class Class 3593

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Mitogen-activated protein kinase 11 and Mitogen-activated prot... 10 31
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Estrogen receptor beta and Peroxisome proliferator-activated r... 1 1
Insulin receptor and Tyrosine-protein kinase Lck ligand AGN-PC... 1 1
Prelamin-A/C and Niemann-Pick C1 protein inhibitor CHEMBL13592... 1 16
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Melanin-concentrating hormone receptor 1 and Muscarinic acetyl... 8 2
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand N-... 2 17
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 7 11
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Mitogen-activated protein kinase 14 inhibitor N-[4-methyl-3-[6... 1 1
Tyrosine-protein kinase ITK/TSK inhibitor SureCN6632543 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446074 CHEMBL520432 Bioactive AGN-PC-04XL74

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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