CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM182
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor (4R)-3-[4-(benzylamino)quinazolin-7-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00308470 Functional Category Bioactive
Superfamily Prelamin-A/C and Insulin receptor Binder Superfamily
Class Class 1053

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Transient receptor potential cation channel subfamily V member... 15 457
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family 10 8
Mitogen-activated protein kinase 1 and Cytochrome P450 3A4 inh... 1 0
RAC-alpha serine/threonine-protein kinase inhibitor 2-[(3,4-di... 3 1
Dihydrofolate reductase inhibitor 1-[3-(2,4-diaminoquinazolin-... 2 4
Substance-P receptor ligand 2-[3,5-bis(trifluoromethyl)phenyl]... 3 1
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 3 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 2
Succinate receptor 1 ligand N-[[4-(3-methylphenyl)phenyl]methy... 2 14
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 2
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Proto-oncogene tyrosine-protein kinase Src and Mast/stem cell ... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 7 2
Epidermal growth factor receptor ligand (E)-1-[4-(3-bromoanili... 9 0
P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(quinolin... 3 3
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308470 CHEMBL103976 Bioactive (4R)-3-[4-(benzylamino)quinazolin-7-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543