CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18205
Family Name Prostaglandin E synthase inhibitor 2-[6-(2-cyclopropylethoxy)-9-(2-hydroxy-2-methylpropyl)-1H-phenanthro[9,10-d]imidazol-2-yl]benzene-1,3-dicarbonitrile family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00446089 Functional Category Bioactive
Superfamily Prostaglandin E synthase Binder Superfamily 3
Class Class 975

Cousin Family NamesSeedsMembers
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 7-et... 7 57
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Transient receptor potential M8 protein ligand (3E)-3-[5-[2-(t... 4 2


External ID

Functional Category

Molecule Name

CFAMM00446091 CHEMBL567493 Bioactive AGN-PC-014YXZ
CFAMM00446090 CHEMBL565617 Bioactive AGN-PC-07CRLH
CFAMM00446089 CHEMBL521285 Bioactive 2-[6-(2-cyclopropylethoxy)-9-(2-hydroxy-2-methylpropyl)-1H-phenanthro[9,10-d]imidazol-2-yl]benzene-1,3-dicarbonitrile
CFAMM00446094 CHEMBL567696 Bioactive AGN-PC-07CRLD
CFAMM00446093 CHEMBL565406 Bioactive AGN-PC-014YVW
CFAMM00446092 CHEMBL585310 Bioactive AGN-PC-014YTZ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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