CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18211
Family Name Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00446112 Functional Category Bioactive
Superfamily Prelamin-A/C and Aurora kinase A Binder Superfamily
Class Class 3526

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
Aurora kinase A Inhibitor MLN8054 Family 2 5
MK-6096 family 3 69
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Wee1-like protein kinase and ALK tyrosine kinase receptor liga... 1 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6j family 2 1
Aurora kinase A inhibitor 4-[[4-(2-chloroanilino)pyrimidin-2-y... 1 0
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Aurora kinase B and Aurora kinase A inhibitor 2-fluoro-6-metho... 2 0
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0Z0U... 2 0
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
C-C chemokine receptor type 5 ligand 4-[[5-[[4-[(5R)-5-(3-chlo... 1 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Ephrin type-A receptor 3 and Tyrosine-protein kinase Fgr ligan... 1 3
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Tyrosine-protein kinase Lck inhibitor SureCN374434 family 1 1
Vascular endothelial growth factor receptor 2 ligand pyrimidin... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand N-benz... 3 12
Signal transducer and activator of transcription 6 inhibitor A... 4 0
Signal transducer and activator of transcription 6 inhibitor 2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446114 CHEMBL522941 Bioactive AGN-PC-072X7P
CFAMM00446113 CHEMBL523991 Bioactive 3h0y
CFAMM00446112 CHEMBL521949 Bioactive AGN-PC-071H3F

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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