CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18214
Family Name Acyl-CoA desaturase inhibitor SureCN1182719 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00446122 Functional Category Bioactive
Superfamily Acyl-CoA desaturase and Tyrosine-protein kinase ITK/TSK Binder Superfamily
Class Class 4773

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Smoothened homolog Inhibitor LDE225 Family 3 76
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 10
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
C-C chemokine receptor type 5 ligand (2,4-dimethyl-1-oxidopyri... 5 4
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 1 18
Gonadotropin-releasing hormone receptor ligand 1-[(2,6-difluor... 6 31
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 3 5
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-[3-cy... 2 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-... 1 5
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Egl nine homolog 1 inhibitor 2-(2-methoxy-4-phenylphenyl)-8-[(... 1 0
Transient receptor potential cation channel subfamily V member... 6 1
Gonadotropin-releasing hormone receptor ligand 2-tert-butyl-8-... 6 23
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 0
Acyl-CoA desaturase inhibitor SureCN1182546 family 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446122 CHEMBL522160 Bioactive SureCN1182719

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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