CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18263
Family Name Inositol monophosphatase 1 and Prelamin-A/C inhibitor GNF-Pf-3828 family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00236364 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor Ligand Terazosin Superfamily
Class Class 211

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 15 18
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 22
cAMP-specific 3',5'-cyclic phosphodiesterase 4C and cAMP-speci... 12 2
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
Alpha-1A adrenergic receptor ligand 4-[4-(4-amino-6,7-dimethox... 3 0
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(o... 4 4
Platelet-derived growth factor receptor beta and Receptor-type... 5 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 0
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0
Aurora kinase A inhibitor AGN-PC-0760BB family 1 1
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Cholinesterase and Acetylcholinesterase inhibitor tacrine deri... 10 0
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Nuclear receptor ROR-gamma and Prelamin-A/C ligand ST50133141 ... 1 0
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PI... 4 0
Macrophage colony-stimulating factor 1 receptor ligand 4-(2,3-... 12 7
Macrophage colony-stimulating factor 1 receptor ligand 4-(3-ch... 5 4
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Survival motor neuron protein inhibitor CHEMBL1496852 family 1 1
Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma ligand ... 1 2
Vascular endothelial growth factor receptor 2 and Serine/threo... 4 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

41322 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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