CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18267
Family Name Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor ionotropic, NMDA 2A ligand (1E)-N'-[(2,6-dimethoxyphenyl)methyl]-1-indol-2-ylidenemethanediamine;hydrochloride family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00446264 Functional Category Bioactive
Superfamily Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-indole-5-carboxamidine Superfamily
Class Class 731

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Apricoxib family 8 77
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
D(2) dopamine receptor Ligand SLV-314 Family 19 69
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Prostaglandin G/H synthase 2 Inhibitor 5-methoxy-2-(4-(methyls... 3 12
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Glucocorticoid receptor and Progesterone receptor ligand AGN-P... 9 6
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
D(2) dopamine receptor ligand SureCN10575660 family 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446264 CHEMBL534486 Bioactive (1E)-N'-[(2,6-dimethoxyphenyl)methyl]-1-indol-2-ylidenemethanediamine;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26820 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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