CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18276
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-009EMK family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00446291 Functional Category Bioactive
Superfamily Beta-lactamase and Integrin beta-3 Binder Superfamily 2
Class Class 1938

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
DNA Binder Chlorambucil Family 3 11
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Tyrosine-protein phosphatase non-receptor type 1 Ligand [[4-(a... 1 7
Integrin beta-3 Inhibitor Xemilofiban Family 2 23
Integrin beta-3 Inhibitor Orbofiban Family 4 25
Integrin beta-3 Inhibitor L-767679 Family 3 6
Integrin beta-3 Inhibitor L-750034 Family 7 38
Integrin beta-3 Inhibitor Lotrafiban Family 5 1
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Free fatty acid receptor 1 ligand AGN-PC-03ZC6J family 2 14
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[(3R)-1... 1 2
Integrin beta-1 and Integrin alpha-5 inhibitor (Z)-2-[1-[(4-am... 1 1


External ID

Functional Category

Molecule Name

CFAMM00446291 CHEMBL536269 Bioactive AGN-PC-009EMK
CFAMM00446292 CHEMBL537409 Bioactive AGN-PC-00J2WU

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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