CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1828
Family Name 5-hydroxytryptamine receptor 4 ligand AGN-PC-00GB52 family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00327879 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 4 and Corticotropin-releasing factor receptor 1 Binder Superfamily
Class Class 3457

Cousin Family NamesSeedsMembers
Aurora kinase A Inhibitor MLN8054 Family 2 5
5-hydroxytryptamine receptor 4 ligand 2-(4-pyridin-4-ylpiperaz... 2 1
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
Aurora kinase A inhibitor 4-[[4-(2-chloroanilino)pyrimidin-2-y... 1 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 3 3
5-hydroxytryptamine receptor 4 ligand 4-amino-5-chloro-N-[1-[8... 2 2


External ID

Functional Category

Molecule Name

CFAMM00327877 CHEMBL332553 Bioactive 2-(4-pyridin-2-ylpiperazin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
CFAMM00327883 CHEMBL121913 Bioactive 2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
CFAMM00327881 CHEMBL121776 Bioactive 2-(4-pyrazin-2-ylpiperazin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
CFAMM00327879 CHEMBL125926 Bioactive AGN-PC-00GB52
CFAMM00327878 CHEMBL125716 Bioactive 2-[4-(2-chloropyrimidin-5-yl)piperazin-1-yl]ethyl 4-amino-5-chloro-2-methoxybenzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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