CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18297
Family Name Melanin-concentrating hormone receptor 1 ligand 2-(3,4-difluorophenyl)-N-ethyl-N-[3-(5-fluorospiro[1H-2-benzofuran-3,4'-piperidine]-1'-yl)propyl]-2-(4-methylsulfonyl-2-oxopiperazin-1-yl)acetamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00446382 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter Inhibitor [n-[2-[(3'-n'-propyl-3''alpha-(bis(4-fluororphenyl)methoxy)tropane-2''beta-carbo Xylic Acid Methyl Ester)(2-mercaptoethyl)amino]acetyl]-2-aminoethanethiolato]rhe Nium(v) Oxide (diastereomeric Mix) Superfamily
Class Class 237

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Neutrophil elastase and Chymotrypsin-C inhibitor benzyl N-[6-(... 3 6
Sigma non-opioid intracellular receptor 1 ligand SureCN5315520... 3 11
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Renin and Potassium voltage-gated channel subfamily H member 2... 6 0
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 4 6
C-C chemokine receptor type 5 ligand benzyl N-[1-[(4S)-4-(cycl... 1 0
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446384 CHEMBL558305 Bioactive 2-(3,4-difluorophenyl)-N-ethyl-N-[3-(5-fluorospiro[1H-2-benzofuran-3,4'-piperidine]-1'-yl)propyl]-2-(2-oxopiperazin-1-yl)acetamide
CFAMM00446383 CHEMBL555055 Bioactive AGN-PC-07C60G
CFAMM00446382 CHEMBL538424 Bioactive 2-(3,4-difluorophenyl)-N-ethyl-N-[3-(5-fluorospiro[1H-2-benzofuran-3,4'-piperidine]-1'-yl)propyl]-2-(4-methylsulfonyl-2-oxopiperazin-1-yl)acetamide
CFAMM00446381 CHEMBL538425 Bioactive SureCN13315595

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27649 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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