CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18298
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B inhibitor AGN-PC-03P5OR family
No. of Seeds 7 No. of Other Members 2
Family Centroid CFAMM00446390 Functional Category Bioactive
Superfamily cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Binder Superfamily
Class Class 2714

Cousin Family NamesSeedsMembers
Multidrug resistance-associated protein 1 Inhibitor Biricodar ... 6 40
Renin Inhibitor CP-305202 Family 9 30
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
cGMP-specific 3',5'-cyclic phosphodiesterase and Cytochrome P4... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 13 0
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Caspase-1 inhibitor (3S)-3-[[2-[3-(naphthalene-2-carbonylamino... 1 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
Pol polyprotein inhibitor Tertiary Amide deriv. 58 family 1 0
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 1 18


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446392 CHEMBL541818 Bioactive AGN-PC-07C1UY
CFAMM00446390 CHEMBL553371 Bioactive AGN-PC-03P5OR
CFAMM00446389 CHEMBL538498 Bioactive AGN-PC-07C1TS
CFAMM00446388 CHEMBL72423 Bioactive methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridin-2-ylethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate
CFAMM00446387 CHEMBL542878 Bioactive AGN-PC-07BZ64

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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