CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18302
Family Name Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN929502 family
No. of Seeds 19 No. of Other Members 2
Family Centroid CFAMM00284666 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Binder Superfamily 14
Class Class 2579

Cousin Family NamesSeedsMembers
Kinetin family 2 39
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
MK-3328 family 2 32
MK-6096 family 3 69
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Serine/threonine-protein kinase Chk1 Inhibitor N-(5,6-diphenyl... 9 100
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 1 3
Coagulation factor X and Prothrombin Inhibitor BMS-344577 Family 13 12
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Sodium-dependent serotonin transporter Inhibitor 4-furan-2-yl-... 2 10
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 1
Gonadotropin-releasing hormone receptor ligand AGN-PC-034WF4 f... 8 23
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 4 2
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Ferritin light chain and Ras-related protein Rab-9A inhibitor ... 1 11
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 5 8
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Adenosine receptor A2a ligand 5-N-[[(2R)-1-[(2-chloro-3,6-difl... 7 9
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 5
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 6 1
Histamine H4 receptor ligand 8-fluoro-4-[(3R)-3-(methylamino)p... 6 1
Adenosine receptor A2a ligand 9-[(6-chloro-1,3-benzodioxol-5-y... 1 0
Histamine H3 receptor ligand 2-(4-piperidin-1-ylpiperidin-1-yl... 1 3
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 0
Scavenger receptor class B member 1 ligand 2-[9-[3-(4,6-dimeth... 1 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
P2X purinoceptor 7 inhibitor SureCN110566 family 1 0
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Adenosine receptor A2a ligand 3-[(2-bromophenyl)methyl]-8-(fur... 2 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 25 5
Adenosine receptor A2a and Adenosine receptor A1 ligand 1-[(2-... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-075YVI ... 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 3 0
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-03J2ZU f... 1 2
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 1 2
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1
Adenosine receptor A2a and Adenosine receptor A1 ligand triazi... 3 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Fatty-acid amide hydrolase 1 inhibitor (Z)-1-(4-pyrimidin-4-yl... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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