CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18316
Family Name Progesterone receptor ligand SureCN3031001 family
No. of Seeds 8 No. of Other Members 40
Family Centroid CFAMM00446479 Functional Category Bioactive
Superfamily Integrin beta-2 and Androgen receptor Binder Superfamily
Class Class 3044

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 23
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
Melanocortin receptor 4 ligand tert-butyl 4-[(3S)-4-[4-[2-[1-[... 2 6
Dipeptidyl peptidase 4 inhibitor SureCN296150 family 3 8
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-050YWL family 2 4
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GBV family 1 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Progesterone receptor ligand SureCN3028669 family 3 9
Progesterone receptor and Androgen receptor ligand SureCN30281... 2 0
Progesterone receptor ligand SureCN13238927 family 1 0
Progesterone receptor and Cytochrome P450 2C9 ligand methyl (3... 3 0
Progesterone receptor and Cytochrome P450 2C9 ligand SureCN303... 2 0
Progesterone receptor and Cytochrome P450 2C9 ligand 2-chloro-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00446484 CHEMBL551541 Bioactive SureCN3021240
CFAMM00446483 CHEMBL559327 Bioactive SureCN3013776
CFAMM00446489 CHEMBL552023 Bioactive SureCN3012539
CFAMM00446479 CHEMBL551885 Bioactive SureCN3031001
CFAMM00446482 CHEMBL592532 Bioactive 2-chloro-4-[(2-methylphenyl)methyl-[(3S)-1-propanoylpyrrolidin-3-yl]amino]benzonitrile
CFAMM00446495 CHEMBL565022 Bioactive SureCN3019171
CFAMM00446481 CHEMBL540476 Bioactive SureCN3031032
CFAMM00446486 CHEMBL539459 Bioactive AGN-PC-07C6GR

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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