CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18339
Family Name Serine/threonine-protein kinase Chk1 inhibitor 3-(2-hydroxypropan-2-yl)-9-(pyridin-4-ylamino)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00446790 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 Binder Superfamily 10
Class Class 4628

Cousin Family NamesSeedsMembers
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-chlorophenyl)-5-... 2 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Serine/threonine-protein kinase Chk1 inhibitor Chk1_97 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446791 CHEMBL564542 Bioactive Chk1_125
CFAMM00446790 CHEMBL540756 Bioactive 3-(2-hydroxypropan-2-yl)-9-(pyridin-4-ylamino)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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