CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1834
Family Name Type-1A angiotensin II receptor and Type-1B angiotensin II receptor ligand methyl 4-[[2-butyl-5-[(Z)-(1,3-dibutyl-2,5-dioxoimidazolidin-4-ylidene)methyl]imidazol-1-yl]methyl]benzoate family
No. of Seeds 7 No. of Other Members 11
Family Centroid CFAMM00091068 Functional Category Bioactive with Natural Product
Superfamily Type-1B angiotensin II receptor and Type-1A angiotensin II receptor Binder Superfamily
Class Class 1526

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Eluxadoline family 4 85
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 3
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 5 0
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 6
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,... 6 15
Vascular endothelial growth factor receptor 2 and Vascular end... 1 0
Thromboxane-A synthase inhibitor SureCN11474904 family 1 6
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Type-1 angiotensin II receptor ligand AGN-PC-025PHO family 3 21


External ID

Functional Category

Molecule Name

CFAMM00327929 CHEMBL341032 Bioactive methyl 4-[[2-butyl-5-[(Z)-(1-butyl-2,5-dioxo-3-pentylimidazolidin-4-ylidene)methyl]imidazol-1-yl]methyl]benzoate
CFAMM00327934 CHEMBL331519 Bioactive SureCN9168938
CFAMM00327927 CHEMBL341151 Bioactive methyl 4-[[2-butyl-5-[(Z)-[1-butyl-2,5-dioxo-3-(4,4,4-trifluorobutyl)imidazolidin-4-ylidene]methyl]imidazol-1-yl]methyl]benzoate
CFAMM00327933 CHEMBL125454 Bioactive methyl 2-[4-[[2-butyl-5-[(E)-(3-butyl-2,5-dioxoimidazolidin-4-ylidene)methyl]imidazol-1-yl]methyl]phenyl]benzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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