CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18353
Family Name Sodium-dependent dopamine transporter and Transporter inhibitor (1R)-3-(3,4-dichlorophenyl)-4-methoxy-N-methyl-2,3-dihydro-1H-inden-1-amine;hydrochloride family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00294693 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor 1-(3,4-dichloro-phenyl)-3-methylamino-indan-5-ol Superfamily
Class Class 1325

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
CORT-108297 family 46 44
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 9
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Dipeptidyl peptidase 4 inhibitor SureCN8267584 family 1 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Transporter and Sodium-dependent serotonin transporter inhibit... 1 0


External ID

Functional Category

Molecule Name

CFAMM00446852 CHEMBL554033 Bioactive (2S,3S)-1-(3,4-dichlorophenyl)-5-methoxy-3-(methylamino)-2,3-dihydro-1H-inden-2-ol;hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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