CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18366
Family Name Lanosterol synthase inhibitor AGN-PC-07BZTC family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00446940 Functional Category Bioactive
Superfamily Lanosterol synthase and Lysosomal alpha-glucosidase Binder Superfamily
Class Class 4104

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Vitamin K epoxide reductase complex subunit 1 Inhibitor Acenoc... 2 46
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 6-nitr... 5 19
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 4 65
Histamine H3 receptor ligand SureCN2785624 family 2 0
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 1 1
Retinoic acid receptor RXR-gamma and Retinoic acid receptor RX... 3 36
Thioredoxin glutathione reductase and Microtubule-associated p... 1 2
Thioredoxin glutathione reductase and Muscleblind-like protein... 1 2
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 4-[3... 4 0
2-[4-(dimethylamino)benzylidene]-6-methoxybenzo[de]chromen-3(2... 1 0
nitrobenzoate NP 2-[(2e)-3-(2-fluorophenyl)prop-2-enoyl]-4-met... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446940 CHEMBL542453 Bioactive AGN-PC-07BZTC

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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