CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18367
Family Name 5-hydroxytryptamine receptor 1A ligand 8-[4-[[(2R)-8-acetyl-5-fluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00446944 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Menin Binder Superfamily
Class Class 1062

Cousin Family NamesSeedsMembers
Bavisant family 9 65
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
C-C chemokine receptor type 5 ligand AC1L9USC family 3 2
Kappa-type opioid receptor ligand 6-[2-oxo-2-[(2S)-2-(pyrrolid... 6 4
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 3 1
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
5-hydroxytryptamine receptor 1A ligand [(7S,8R)-7-(dipropylami... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00446944 CHEMBL542474 Bioactive 8-[4-[[(2R)-8-acetyl-5-fluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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