CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18395
Family Name 5-hydroxytryptamine receptor 1A ligand 8-[4-[[(2S)-5-fluoro-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00447041 Functional Category Bioactive
Superfamily Beta-lactamase and Histamine H3 receptor Binder Superfamily
Class Class 3198

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Estradiol 17-beta-dehydrogenase 1 Inhibitor N-n-diethyl Estrad... 6 16
Estradiol 17-beta-dehydrogenase 1 Inhibitor N-ethyl Estrone-16... 3 5
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 4
Delta-type opioid receptor ligand N-[(7S)-5-(3-hydroxyphenyl)-... 9 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447042 CHEMBL555356 Bioactive 8-[4-[[(2R)-5-fluoro-8-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride
CFAMM00447041 CHEMBL544838 Bioactive 8-[4-[[(2S)-5-fluoro-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride
CFAMM00447040 CHEMBL558994 Bioactive 8-[4-[[(2R)-5-fluoro-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride
CFAMM00447039 CHEMBL555098 Bioactive [(7R)-7-[4-(7,9-dioxo-8-azaspiro[4.5]decan-8-yl)butyl-propylamino]-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-yl] trifluoromethanesulfonate;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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