CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM184
Family Name D(4) dopamine receptor ligand AGN-PC-0073PO family
No. of Seeds 7 No. of Other Members 10
Family Centroid CFAMM00308491 Functional Category Bioactive
Superfamily Orexin receptor type 2 and D(4) dopamine receptor Binder Superfamily
Class Class 1140

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Dipeptidyl peptidase 4 Inhibitor (2-chloro-6-phenoxyphenyl)met... 17 24
C-C chemokine receptor type 5 Ligand N-(2-(4-chlorobenzyloxy)-... 3 13
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Inhibitor 2... 1 9
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 3
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[2-... 6 15
Sodium-dependent serotonin transporter inhibitor 3-(3,4-dichlo... 1 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Histamine H3 receptor ligand AGN-PC-0765YW family 1 4
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 4 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 2
Sodium-dependent serotonin transporter inhibitor 4-(4-chloro-2... 2 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
D(4) dopamine receptor ligand 4-[(4-chlorophenyl)methyl]-2-[(2... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 0
Voltage-dependent T-type calcium channel subunit alpha-1G and ... 1 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308494 CHEMBL104035 Bioactive AGN-PC-009N9E
CFAMM00308500 CHEMBL105696 Bioactive AGN-PC-007SNB
CFAMM00308493 CHEMBL108122 Bioactive AGN-PC-01VJHL
CFAMM00308498 CHEMBL104550 Bioactive SureCN6160084
CFAMM00308491 CHEMBL105181 Bioactive AGN-PC-0073PO
CFAMM00308496 CHEMBL107691 Bioactive AGN-PC-0065NX
CFAMM00308502 CHEMBL104801 Bioactive 4-[(4-chlorophenyl)methyl]-2-[(2-ethoxyphenoxy)methyl]-1,4-oxazepane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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