CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18409
Family Name Cathepsin L1 and Cathepsin L2 inhibitor 5-tert-butyl-N-[(2S)-1-(cyanomethylamino)-1-oxo-3-[3-(1,3,4-thiadiazol-2-yl)phenyl]propan-2-yl]-2-methylpyrazole-3-carboxamide family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00447070 Functional Category Bioactive
Superfamily Cathepsin L2 and Cathepsin S Binder Superfamily
Class Class 3713

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
5-hydroxytryptamine receptor 2A ligand AGN-PC-04RTMN family 7 5
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
cAMP-dependent protein kinase catalytic subunit PRKX and Rho-a... 1 1
Cathepsin S and Cathepsin L2 inhibitor N-[(2S)-1-(cyanomethyla... 1 0
P2X purinoceptor 3 inhibitor N-[1-(4-acetylpiperazin-1-yl)prop... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447070 CHEMBL549378 Bioactive 5-tert-butyl-N-[(2S)-1-(cyanomethylamino)-1-oxo-3-[3-(1,3,4-thiadiazol-2-yl)phenyl]propan-2-yl]-2-methylpyrazole-3-carboxamide
CFAMM00447068 CHEMBL562844 Bioactive 5-tert-butyl-N-[(2S)-1-(cyanomethylamino)-3-[3-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl]-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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