CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18410
Family Name Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[2-(1H-benzimidazol-2-ylsulfanyl)-5-nitro-2,3-dihydroinden-1-ylidene]amino]guanidine family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00447086 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Retinal dehydrogenase 1 Binder Superfamily
Class Class 3644

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
Tryptase Inhibitor Babim Family 12 90
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Sterol O-acyltransferase 1 inhibitor 1-(2,4-difluorophenyl)-3-... 8 90
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2
Carbonic anhydrase 7 and Carbonic anhydrase 13 inhibitor 4-[(4... 1 5
Nociceptin receptor ligand 6-fluoro-2-pentan-3-ylsulfanyl-5-pi... 1 4
Nociceptin receptor ligand 2-[(2,3-dichlorophenyl)methylsulfan... 1 1
Sterol O-acyltransferase 1 inhibitor SureCN9766896 family 4 23
Sterol O-acyltransferase 1 inhibitor AGN-PC-075SUK family 1 0
Sterol O-acyltransferase 1 inhibitor AGN-PC-025JYX family 1 1
Small conductance calcium-activated potassium channel protein ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447075 CHEMBL549392 Bioactive 2-[(E)-[2-(1H-benzimidazol-2-ylsulfanyl)-2,3-dihydroinden-1-ylidene]amino]guanidine;hydrochloride
CFAMM00447086 CHEMBL560806 Bioactive 2-[(E)-[2-(1H-benzimidazol-2-ylsulfanyl)-5-nitro-2,3-dihydroinden-1-ylidene]amino]guanidine
CFAMM00447079 CHEMBL561343 Bioactive 2-[(E)-[2-[(6-nitro-1H-benzimidazol-2-yl)sulfanyl]-2,3-dihydroinden-1-ylidene]amino]guanidine;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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