CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18412
Family Name Histamine H3 receptor ligand SureCN3052824 family
No. of Seeds 4 No. of Other Members 14
Family Centroid CFAMM00447097 Functional Category Bioactive
Superfamily Histamine H3 receptor and Potassium voltage-gated channel subfamily A member 5 Binder Superfamily
Class Class 2121

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Histamine H3 receptor ligand 2-benzyl-4-[4-(2-pyrrolidin-1-yle... 8 4
Androgen receptor ligand 4-[(1R,5R)-3-hydroxy-3-methyl-8-azabi... 8 7
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 3 1
C-C chemokine receptor type 3 ligand CHEMBL300905 family 2 1


External ID

Functional Category

Molecule Name

CFAMM00447097 CHEMBL554495 Bioactive SureCN3052824
CFAMM00447094 CHEMBL563998 Bioactive SureCN3055918

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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