CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18414
Family Name Progesterone receptor and Cytochrome P450 2C19 ligand AGN-PC-07C6YU family
No. of Seeds 8 No. of Other Members 3
Family Centroid CFAMM00446900 Functional Category Bioactive
Superfamily Cytochrome P450 2C19 and Progesterone receptor Binder Superfamily
Class Class 3473

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
Benzodiazepine receptor Ligand Alprazolam Family 4 35
Benzodiazepine receptor Ligand Midazolam Family 5 160
14-alpha sterol demethylase Inhibitor Butoconazole Family 2 53
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
HCV NS4B protein Inhibitor Clemizole Family 2 43
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 2 1
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(3,4-dich... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Progesterone receptor and Cytochrome P450 2C19 ligand AGN-PC-0... 6 13
ATP synthase subunit beta, mitochondrial and ATP synthase subu... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447119 CHEMBL552108 Bioactive AGN-PC-07C5YK
CFAMM00447118 CHEMBL555562 Bioactive AGN-PC-0727FA
CFAMM00447124 CHEMBL559580 Bioactive AGN-PC-07C4IV
CFAMM00447120 CHEMBL549554 Bioactive 2-chloro-4-[(2-chlorophenyl)methyl-[1-(4,5-dimethyl-1,2,4-triazol-3-yl)ethyl]amino]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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