CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18420
Family Name Nociceptin receptor and Mu-type opioid receptor ligand (1S,5S)-8-[bis(2-chlorophenyl)methyl]-3-(6-methylpyridin-2-yl)-8-azabicyclo[3.2.1]octane family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00447167 Functional Category Bioactive
Superfamily Nociceptin receptor and Mu-type opioid receptor Binder Superfamily 4
Class Class 471

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Sarcoplasmic/endoplasmic reticulum calcium ATPase inhibitor qu... 2 60
Transient receptor potential cation channel subfamily V member... 16 295
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 2 1 2
Histamine H1 receptor and Cytochrome P450 2D6 ligand 2-[3-[(1R... 1 10
Corticotropin-releasing factor receptor 1 ligand N-(cyclopropy... 2 2
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloro-4-fl... 6 7
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 5
Neuronal acetylcholine receptor subunit alpha-2 and Neuronal a... 2 0
Neuropeptide Y receptor type 5 ligand SureCN4464548 family 17 2
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 17
Nociceptin receptor and Mu-type opioid receptor ligand N-[(1R,... 4 2
Nociceptin receptor and Mu-type opioid receptor ligand (1S,5S)... 1 0
Corticotropin-releasing factor receptor 1 ligand 2-(2,4-dichlo... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447167 CHEMBL549690 Bioactive (1S,5S)-8-[bis(2-chlorophenyl)methyl]-3-(6-methylpyridin-2-yl)-8-azabicyclo[3.2.1]octane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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