CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18422
Family Name Cathepsin L1 and Cathepsin L2 inhibitor 5-tert-butyl-N-[(2S)-1-(cyanomethylamino)-3-[3-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00447381 Functional Category Bioactive
Superfamily Cathepsin L1 and Cathepsin L2 Binder Superfamily
Class Class 3168

Cousin Family NamesSeedsMembers
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 4 2
Histone-arginine methyltransferase CARM1 inhibitor BMS pyrazol... 1 3
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 15 1
Histone-arginine methyltransferase CARM1 inhibitor SureCN14565... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447382 CHEMBL549791 Bioactive 5-tert-butyl-N-[(2S)-1-(cyanomethylamino)-3-[3-[5-(hydroxymethyl)-1,3,4-oxadiazol-2-yl]phenyl]-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide
CFAMM00447381 CHEMBL550872 Bioactive 5-tert-butyl-N-[(2S)-1-(cyanomethylamino)-3-[3-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide
CFAMM00447385 CHEMBL555122 Bioactive N-[(2S)-3-[3-[5-(2-aminoethyl)-1,3,4-oxadiazol-2-yl]phenyl]-1-(cyanomethylamino)-1-oxopropan-2-yl]-5-tert-butyl-2-methylpyrazole-3-carboxamide
CFAMM00447384 CHEMBL554065 Bioactive 5-tert-butyl-N-[(2S)-1-(cyanomethylamino)-3-[3-[5-(methoxymethyl)-1,3,4-oxadiazol-2-yl]phenyl]-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide
CFAMM00447383 CHEMBL557455 Bioactive N-[(2S)-3-[3-[5-(aminomethyl)-1,3,4-oxadiazol-2-yl]phenyl]-1-(cyanomethylamino)-1-oxopropan-2-yl]-5-tert-butyl-2-methylpyrazole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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