CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18429
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-04T8FI family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00447419 Functional Category Bioactive
Superfamily cGMP-specific 3',5'-cyclic phosphodiesterase Binder Superfamily 6
Class Class 877

Cousin Family NamesSeedsMembers
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
GDC-0349 family 44 77
JAK Inhibitor Momelotinib Family 33 83
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Amine oxidase [flavin-containing] A Inhibitor 3-benzyl-n-(2-mo... 2 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family 13 8
Serine/threonine-protein kinase mTOR and RAC-alpha serine/thre... 3 3
Neuropeptide Y receptor type 5 ligand 8-[[[6-(2-fluorophenyl)p... 4 0
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Mitogen-activated protein kinase 1 and Cytochrome P450 3A4 inh... 1 0
Glucosylceramidase and Alpha-galactosidase A inhibitor AC1NNEG... 4 5
Prothrombin and Trypsin-1 inhibitor SureCN12636557 family 9 1
Prelamin-A/C and Cellular tumor antigen p53 inhibitor CHEMBL16... 1 7
Toll-like receptor 7 ligand 4-amino-1-[[6-[(2S)-2-(pyrrolidin-... 4 0
Transient receptor potential cation channel subfamily V member... 2 1
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... 4 0
Transient receptor potential cation channel subfamily V member... 4 0
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 2
Serine/threonine-protein kinase mTOR inhibitor 2-[4-[4-[(3S)-3... 3 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Prothrombin inhibitor AGN-PC-073GVF family 12 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447414 CHEMBL557059 Bioactive AGN-PC-07C6R8
CFAMM00447419 CHEMBL550007 Bioactive AGN-PC-04T8FI
CFAMM00447418 CHEMBL557467 Bioactive AGN-PC-07C6RF
CFAMM00447415 CHEMBL559889 Bioactive AGN-PC-07C3TR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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