CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18443
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand 3,5-dimethyl-4-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]sulfonylmorpholine family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00447474 Functional Category Bioactive
Superfamily Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 2606

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(4-... 4 7
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (1S,5... 2 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 6
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 6 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 14 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447471 CHEMBL550405 Bioactive N-(2-methoxyethyl)-4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]benzenesulfonamide
CFAMM00447469 CHEMBL559118 Bioactive 4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-N-(oxan-4-yl)benzenesulfonamide
CFAMM00447468 CHEMBL554506 Bioactive 4-methoxy-1-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]sulfonylpiperidine
CFAMM00447474 CHEMBL561279 Bioactive 3,5-dimethyl-4-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]sulfonylmorpholine
CFAMM00447473 CHEMBL564380 Bioactive SureCN14302697

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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